Mitochondrial Processing Peptidase

A hetero-dimeric protein consisting of two subunits, alpha and beta, which are referred to as PMPCA and PMPCB in humans. It plays an essential role in removing the N-terminal targeting peptidase from precursor proteins imported into the mitochondria.

Also Known As:

alpha-MPP; beta-MPP; Peptidase, Matrix Processing; Peptidase, Mitochondrial Processing; Processing Peptidase, Matrix; Processing Peptidase, Mitochondrial; Processing Protease, Mitochondrial; Protease, Mitochondrial Processing; alpha MPP; beta MPP; Matrix Processing Peptidase; Mitochondrial Processing Protease

Enzymes and Coenzymes: 1
- Enzymes: 155591
  - Hydrolases: 2206
    - Peptide Hydrolases: 24289
      - Metalloproteases: 8398
        Metalloendopeptidases: 70
        Mitochondrial Processing Peptidase: 5
      - Endopeptidases: 643
        Metalloendopeptidases: 70
        Mitochondrial Processing Peptidase: 5
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Mitochondrial Proteins: 1859
    - Mitochondrial Processing Peptidase: 5

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Disease

Drug/Important Bio-Agent (IBA)